Phase I Trials Platform in Oncology, CITOHL

Assistant of the university service, she is in charge of the secretariat, of the management of the bibliographical database. She is the link between the clinical, university and analytical teams

Gilles Freyer, Professor of Cancer research in the South Lyon Hospital, is also a doctor in Sciences and graduate of in-depth studies in biological and medical ethics of the university Paris - Necker. Beside his activity in hospital, he leads an activity of research and teaching. As for the research he pilots the trial platform of phase I in cancer research which implies the service of Medical Oncology of the South Lyon Hospital and the team "Modelisation of tumor biology and optimisation cancer drug effects", the constituent of the EMR 3738 " Chemotherapy Targeting in Oncology " (director: Pr François-Noël GILLY, UFR Lyon-South Charles Mérieux, UCB Lyon 1). As regards the education, Gilles Freyer teaches the clinical cancer research and the human and social sciences at the University Lyon I. He is the author of various books of whom "Faire face au Cancer: l'espoir au quotidien".

Benoit You is an academic staff physician working within Medical Oncology Department and Onco-Hematology phase 1 trial Unit at Centre Hospitalier Lyon-Sud. He is in charge of the medical oncology trials developed in collaboration with pharmacokinetic-pharmacodynamic laboratory (EMR 3738) of Faculté de médicine Lyon-Sud Charles Mérieux (Université Claude Bernard Lyon 1).
Graduated from Université Claude Bernard Lyon 1 (France) in 2008, he is a medical oncologist. He has focused his research activity toward pharmacology (PK-PD), mathematic modeling, tumor marker kinetics and early drug development (phase I and phase II trials). During a 18 month fellowship at Drug Development Program of Princess Margaret Hospital (Toronto, Canada), one of the phase 1 trial centers funded by the US National Cancer Institute, Benoit You improved his skills in phase 1 trial designing and leading. Moreover he established strong collaborations with international collaborative groups including National Cancer Institute of Canada and Gynecology Oncology Group.
He is the first author of 8 pharmacology, modeling or drug development-related articles published in international journals. To lead his research projects, he has received 11 grants or awards including the Bourse Walter-Zelidja from Académie Française and Fellowship award from Ontario Institute for Cancer Research.

Olivier Colomban (MSc in Applied Mathematics), Applied Mathematics and Modeling Engineer at University Claude Bernard Lyon 1, Biostatistician. After studies in mathematics and statistics he joined the EMR 3738 team in 2008. He is specialized in PK/PD modeling and biomarker analysis in oncology. In the past he was statistician at Mapi Registrat CRO (ex-Mapi Naxis) where he honed his skills in the analysis of clinical trials of late phases. Further clinical research he's the IT Manager of the unit.

Bio-engineer